Indications

Alphachymotrypsin is a proteolytic enzyme that is used in reducing soft– tissue inflammation and edema associated with surgery and trauma.

Present

Blister of 10 tablets. Box of 2 blisters.

Composition

Chymotrypsin (Alphachymotrypsin) …………………………..4200 USP units
(equivalent to 21 microkatals)
Excipients s.q. for……………………………………………………………….1 tablet
(Wheat starch, Sucrose, Peppermint oil, Magnesium stearate).

Contra-Indications

Hypersensitivity to Chymotrypsin and any ingredient of the medicine.

Side effect

– Some digestive disorder cases may occur: flatulence, dyspepsia, diarrhea, nausea.
– Mild allergic reaction may occur with high dosage: erythema.
Inform your doctor about side– effects when using this medicine.

Precaution

– Caution should be exercised in patients with inherited bleeding disorder such as hemophilia, bleeding disorder, on anticoagulant therapy, impending surgery, hypersensitivity to protein, peptic ulcer.
– There is no report of adverse effect on ability to drive and operate machinery.
PREGNANCY AND LACTATION:
Chymotrypsin should not be used for pregnant women and nursing mothers.

Interaction

– Do not coadminister this drug with Acetylcysteine.
– Coadministration with anticoagulants should be avoided because of potentiation of the anticoagulants effects.
OVERDOSAGE:
Should overdosage occur, turn to the nearest healthcare facility for medical attention of the healthcare professionals.

Shelf life

24 months from the manufacturing date.

Storage

Store in a dry place (RH ≤ 70%), not exceeding 30^oC. Protect from light.

Dosage

The tablet may be swallow whole or placed under the tongue until they are dissolved
– Oral dose: 2 tablets, 3 – 4 times daily.
– Sublingual tablet: 4 – 6 tablets/day, in divided doses (the tablet should slowly be dissolved sublingually).